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14, 15 The QELT SVS data was acquired using a short TE 1 H MC-semiLASER (metabolite cycling semi Localization by Adiabatic SElective Refocusing) sequence applying the following parameters 16 : TE = 24 ms, T R = 5 s, 64 averages, 512 ms acquisition time and 8 kHz bandwidth

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A more recent hypothesis postulates that high-dose folic acid redirects the active form of vitamin B12 in serum, i.e., holotranscobalamin, either toward the bone marrow to support reticulocyte synthesis that is induced by folic acid in B12-deficient patients, or into the urine in which it is excreted instead of being taken up and recycled into circulation through the kidneys (84)

haematobium -hamster model [24, 61] and for related trematodes responsible for hepatobiliary tract disease including cholangiocarcinoma [24, 62,63,64,65,66]

"[Because] it is given intravenously, the skin lightening occurs on a cellular level